About the Opportunity

EPM Scientific is partnered with an early-stage clinical biotechnology company advancing a program in hemato-oncology. The company is seeking a Chief Medical Officer (CMO) to report directly to the CEO and provide hands-on medical leadership across its clinical development activities.

This is a fractional executive engagement designed for an experienced clinical development leader who can guide strategy, clinical execution, safety oversight, and regulatory interactions during a critical stage of growth.

Position Details

Title: Chief Medical Officer (CMO)

Reporting To: Chief Executive Officer

Start Date: ASAP

Location: Fully Remote (USA preferred; European candidates will also be considered)

Engagement Type: Freelance / Consultant

Commitment: 0.4–0.6 FTE

Duration: Indefinite

Therapeutic Area: Hemato-Oncology (AML)

Language: English

Key Responsibilities

Provide overall medical oversight and strategic direction for the company's AML clinical development program.

Support and oversee protocol development for upcoming clinical trials, ensuring scientific rigor and regulatory alignment.

Serve as the primary medical contact for Principal Investigators, building strong clinical relationships and supporting site engagement activities.

Oversee safety monitoring activities, including review of adverse events and ongoing safety data throughout the clinical trial lifecycle.

Collaborate closely with the CEO and cross-functional teams to advance clinical milestones and development objectives.

Support interactions with regulatory authorities and contribute to the preparation of clinical and regulatory documentation.

Qualifications

Medical degree (MD or equivalent) required.

Board certification or equivalent training in hematology, oncology, or hemato-oncology is beneficial but not required.

Demonstrated clinical development experience within biotechnology or pharmaceutical organizations, preferably in early-stage development environments.

Direct experience with AML or hemato-oncology clinical trials is required, including familiarity with current treatment landscapes and study design considerations.

Proven track record working with Principal Investigators and the broader clinical community within the therapeutic area.

Comfortable operating in a lean, fast-moving organization where flexibility, initiative, and hands-on leadership are essential.

Strong communication, leadership, and problem-solving skills with the ability to work independently in a remote environment.

Work Structure

Fractional consulting engagement.

0.4–0.6 FTE commitment.

Fully remote.

Long-term, indefinite engagement.

Reports directly to the CEO.

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